Cyriaque Mvourandjiami en pleine audition devant les commissaires de la CNLCEI © D.R
Extraits tôt ce matin de la prison centrale de Libreville, Cyriaque Mvourandjiami, ex tout puissant Directeur de cabinet politique d’Ali Bongo, et Gisèle Mombo, ancien Directeur administratif et financier à la Mairie de Libreville, par ailleurs belle mère de Ian Ghislain Ngoulou, ancien tout puissant Directeur de Cabinet de Noureddin Bongo Valentin, fils ainé de l’ancien Président, Ali Bongo déchu, ont été longuement auditionnés mardi 13 février 2024 par les membres de la Commission nationale de lutte contre la corruption et l’enrichissement illicite (CNLCEI), pour soupçons de corruption.
« Les personnes extraites ce matin viennent pour être auditionnées aujourd’hui et par la suite, relativement aux soupçons de corruption, d’enrichissement illicite et d’autres infractions annexes ou connexes à ces précédentes infractions à caractère financier », a fait savoir Nestor Mbou, président de la CNLCEI.
Pour le haut magistrat président de la commission, ces auditions rentrent dans le cadre de l’accomplissement des missions de son institution. En effet, la CNLCEI a pour missions de sensibiliser, de mener des investigations donc d’enquêtes et de procéder à la consultation. La présente opération répond à la mission d’investigations.
« Il me sied de rappeler que la mission de la commission doit se limiter uniquement à entreprendre les investigations. Une fois les investigations menées à terme, en fonction du résultat, la commission transmet le dossier au procureur de la république, conformément à la loi. La commission n’a pas vocation à juger ; ce n’est pas une juridiction pénale », a-t-il précisé.
Pour ces enquêtes, il y aura près d’une dizaine des personnes qui seront auditionnées par la Commission nationale de lutte contre la corruption et l’enrichissement illicite.
Soupçonnés des détournements massifs de fonds publics, de corruption active, de trafic des stupéfiants, d’association de malfaiteurs, et autres, Cyriaque Mvourandjiami, Ian Ghislain Ngoulou, Noureddin Bongo Valentin, Oceni Ossa Abdul, Mohamed Ali Saliou (puissant directeur de cabinet adjoint d’Ali Bongo), Jessye Ella Ekogha (porte-parole de la présidence) et Gisèle Mombo, ont été placés sous mandat de dépôt au lendemain du coup d’Etat sans effusion de sang encore appelé « coup de libération) intervenu le 30 août 2023.
Sydney IVEMBI
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I’ll get to stacking in a second, however biking these dietary supplements close to
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Legal steroids don’t work like anabolic steroids or artificial testosterone—you
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spot major modifications, even with out altering your exercise.
As a private health coach, I at all times dread coping with feminine bodybuilders when I know they’ve resorted to anabolic steroid use to achieve significant muscle gains.
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It is a safe and effective alternative to the anabolic steroid Deca-Durabolin, which
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Deca Durabolin is a widely known steroid and is even permitted
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named one of the safer anabolic steroids in the marketplace.
Some unwanted aspect effects of Deca Durabolin embody
elevated blood strain, lowered sexual efficiency, and erectile dysfunction (sometimes
called « Deca dick »).
Outcomes range from person to person, with some customers seeing results in even two
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In the Usa, the authorized standing of steroids is outlined by the
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Yes, steroids are illegal within the United States with no prescription. In the United States,
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Anadrol is a steroid that’s more regular among men when contrasted with women. Anadrol is
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to interrupt down and utilize stored fat. Magnesium
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These supplements usually comprise a blend of nutritional vitamins, minerals, amino acids, and natural
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Some people may be interested in taking natural steroid dietary
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Nonetheless, not all-natural steroid alternatives are
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market.
Tradition can be a source of national pride and identification, and also
can affect financial and social growth. But in smaller
doses, caffeine could be a nice supplement while coaching.
There is a danger of making ancient Greek athletes superhuman moral individuals,
but they have been people like us. Nevertheless,
the reviewers notice that these merchandise are difficult to check and evaluate as firms are protective of their individual ingredient blends.
Different complement manufacturers comprise a diversified mixture
of the above ingredients. Nevertheless, the precise amounts of every
ingredient aren’t always clear as firms aren’t open about their formulas.
This perspective emphasizes the significance of non-public liberty and individual rights in a democratic society.
They may depend on them for enhanced performance and experience withdrawal
symptoms after they stop taking them. Some evidence suggests sure particular
person components in exercise dietary supplements can improve muscle-building and bodily performance.
For best outcomes, it ought to be stacked with other legal steroids, as results are minimal with HGH-only cycles
in our experience. The above side effects,
plus the truth that Sustanon 250 is an injectable steroid, can lead to some individuals avoiding this anabolic
steroid.
HyperGH14X is a distinguished HGH releaser focused on selling lean muscle
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There is potentially a large number of AAS users who haven’t been surveyed as they are not accessing native
substance use services or select not to full surveys for fear of
being categorized as ‘junkies’ [60]. Another suggested mechanism leading to neurodegeneration is the impact of testosterone in over-physiological doses on intracellular
calcium metabolism. Testosterone induces intracellular Ca2+ oscillations in the cytosol and cell nucleus, that are important mediators of further transformations, together with neurite progress.
In a number of cell fashions, it has been proven that the intracellular improve of calcium ions can contribute to the induction of apoptosis.
The use of testosterone in low concentrations had no impact on cell viability, however with the gradual improve in testosterone
focus, the viability of nerve cells decreased [116].
Legal steroid alternate options like Testo-Max work to
stimulate your body’s pure testosterone production using natural components and essential vitamins.
Products like D-Bal Max are designed to boost nitrogen retention and boost protein synthesis, allowing your body to rebuild
muscle tissue extra efficiently. When your restoration times
improve, you’re able to carry heavier, prepare longer,
and construct lean muscle faster—without overtraining.
Anvarol accommodates soy and whey concentrates that assist to reduce back fat and boost DHEA ranges, which
helps to spice up testosterone manufacturing naturally.
Where it is identified that customers intend to proceed administering AAS following remedy, it’s important
that they obtain acceptable hurt reduction recommendation, similar to on safe injecting,
blood-borne viruses (BBVs) and AAS cycles.
For example, in seven studies, therapies for infectious problems associating with
injecting AAS were reported. There was no indication of related hurt reduction work included alongside remedy, similar to advice or demonstration referring to injecting or injecting strategies in any of these studies,
aside from Rich and colleagues who reported provision of counselling on the dangers of BBVs [180].
The potential side effects of anabolic steroid misuse are important
and persistent. Well Being care providers should pay consideration to patients
susceptible to anabolic-androgenic steroid misuse.
Ongoing patient schooling about the potential unwanted effects should be
offered for sufferers who take androgens for therapeutic
use. Timely identification of the anabolic steroid abuse
and applicable referral for treatment is very warranted.
Roughly three to 4 million Americans used anabolic-androgenic
steroids to increase muscle mass, whether or not for sports to extend their efficiency or cosmetic functions, corresponding to enhancing their appearance.
People who’ve misused steroids could additionally be suffering from muscle dysmorphia, which is a behavioral
syndrome. AAS are incessantly utilized by fighters, bouncers, and security personnel
to boost their appearance and job efficiency. The popular time period used for
the anabolic steroids is « steroids, » and other widespread names
are « roids, » « juice, » « andro, » « gear, » and « stackers. »
Nonetheless, in continual customers, prolonged duration of hypogonadism and
low testosterone is buying Steroids online illegal observed[23][24][23].
In athletes, androgen use have to be discontinued immediately,
despite the actual fact that withdrawal signs are anticipated.
If initiating testosterone replacement remedy for the remedy of hypogonadism, therapeutic use exemptions from
applicable companies ought to be sought earlier than initiation of
alternative therapies.[1].
In 2021, a research was printed to determine the brain age gap (BAG, brain age gap)
on a bunch of 229 males, in which 130 members had been confirmed to have extended use of AAS based on magnetic resonance imaging (MRI).
The BAG is the distinction between the chronological age and the expected age of the mind.
As the chronological age, a reference to the MRI scans of a
gaggle of 1838 wholesome males aged 18–92 was used.
For all individuals, BAG age was estimated based mostly on features
of the whole brain and its subregions. A statistically significant enhance within the predicted age of the
mind in comparison with the management group was discovered for the frontal,
temporal, crest, cingulate, and occipital
areas in the group of sufferers using AAS for more than 10 years in excessive doses.
In the absence of hormone, it’s by and huge accepted that steroid receptors exist as an inactive
oligomeric advanced, being sequestered by the heat-shock protein (Hsp), Hsp90, which acts as
a molecular chaperone. Hsps are so-called as a result of they have been found to build
up underneath stress situations including within heat-traumatized cells, however many are current and functionally essential under normal conditions; they are named according
to their molecular weight in kilodaltons.
The mechanism of toxicity remains poorly understood, nevertheless it has
been suggested to result from AR activation in liver
cells, leading to an increased manufacturing of reactive oxygen species (ROS) (11).
Therefore, AAS with adequate resistance to hepatic breakdown and efficiency to
activate the AR are prone to incur liver damage.
The scientific relevance of elevated biochemical markers of liver damage
in response to AAS use stays unknown.
However, this doesn’t preclude the chance that these changes may turn into everlasting with extra prolonged
AAS use or with repeated cycles that present too little time
for recovery to take place in between. This is especially worrisome
as there might be considerable evidence that myocardial injury, which may accumulate in years of ongoing AAS use,
is a primary cause for sudden cardiac dying in AAS customers (217).
Since massive doses of AAS are administered throughout an AAS cycle, it is evident that the event of gynecomastia during AAS use is not the results of an absolute or relative deficiency of
androgenic action. Estradiol levels enhance dose-dependently with
testosterone administration; nonetheless, the increase is of
proportionately lesser magnitude with growing doses, indicating saturation of
aromatase activity (23). As such, it appears cheap to conclude that an absolute excess of estrogenic action causes the
event of gynecomastia throughout AAS use, regardless of its relative action in contrast with androgens.
The testicular production of testosterone is governed by the
hypothalamic–pituitary–gonadal axis (HPGA; see Figure 5).
Aside from binding with the steroid, the ligand-binding area additionally functions in dimer formation and mediates transcriptional activation. The
DNA-binding area targets the receptor to specific DNA sequences known as steroid (or hormone) response parts.
On the receptor, the DNA-binding domain consists of two subdomains known as ‘zinc-fingers’;
every subdomain incorporates 4 cysteine residues that coordinate with a zinc atom, thus, stabilizing the ‘finger’ structure.
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